BOC ANHYDRIDE;

tert-butyldicarbonate;

PYROCARBONIC ACID DI-TERT-BUTYL ESTER;

1) in organic synthesis is used to introduce the tert-butyl oxygen carbonyl protection groups.

2) the second tertiary butyl ester carbonate (Boc anhydride) in organic synthesis is used to introduce tert-butyl oxygen carbonyl protection genes, especially used in amino acid amino protection. Widely used in medicine, protein and peptide synthesis, biological chemical synthesis in food, cosmetics and other products.

3) used as a medicine and organic synthesis intermediates, is an important application in medicine and the synthesis of agrochemical products amino protective agent

4) in the organic chemistry reaction, often, phenol, mercaptan as amine, amide, lactam, carbamate and other substrates tert-butyl oxygen carbonylation reagent, the reaction rate quickly, the production rate is high. Tertiary butyl oxidative carbonylation reaction protection (functional groups), Because of acyl halide reagent stability is poorer, so is widely used for the protection of the amino group, the protection groups in acidic conditions (such as hydrochloric acid and trifluoroacetic acid, etc.) can take off. Fatty amine, alicyclic amines, aromatic amine and heterocyclic amines are able to react with (Boc).

5) security: to synthesize a kind of the same as the natural peptide compounds, must take all kinds of optical rotation of amino acids in a certain order to connect with a certain length of peptides, the need to make a kind of amino acid of carboxyl and amino when combined, another kind of amino acid to prevent the same kind of combination between amino acid molecules, as a result, the synthesis, must get certain amino and carboxyl protected, so that reactions can, in accordance with the requirements of the way.

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